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Gadolinium inhibits Na(+)-Ca(2+) exchanger current in guinea-pig isolated ventricular myocytes

The trivalent cation, gadolinium (Gd(3+)) is commonly used to inhibit stretch-activated channels. In this report, we show that Gd(3+) also inhibits ionic current (I(NaCa)), carried by the Na(+)-Ca(2+) exchanger protein. Under selective recording conditions, Gd(3+) inhibited both outward and inward I...

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Detalhes bibliográficos
Main Authors: Zhang, Y H, Hancox, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572111/
https://ncbi.nlm.nih.gov/pubmed/10821774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703353
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