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Proteasome inhibitors uncouple rhesus TRIM5α restriction of HIV-1 reverse transcription and infection

The primate TRIM5α proteins have recently been defined as cellular restriction factors, preventing primate infection by retroviruses from different species. For instance, rhesus TRIM5α (rhTRIM5α) restricts infection by HIV-1. Virtually all TRIM5α proteins block the early replication of retroviruses...

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Autores principales: Wu, Xiaolu, Anderson, Jenny L., Campbell, Edward M., Joseph, Ajith M., Hope, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464362/
https://ncbi.nlm.nih.gov/pubmed/16648264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510483103
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