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Rapid glucose sensing by protein kinase A for insulin exocytosis in mouse pancreatic islets

The role of protein kinase A (PKA) in insulin exocytosis was investigated with the use of two-photon excitation imaging of mouse islets of Langerhans. Inhibitors of PKA selectively reduced the number of exocytic events during the initial period (< 250 s) of the first phase of glucose-induced exoc...

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Detalhes bibliográficos
Main Authors: Hatakeyama, Hiroyasu, Kishimoto, Takuya, Nemoto, Tomomi, Kasai, Haruo, Takahashi, Noriko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464314/
https://ncbi.nlm.nih.gov/pubmed/16284079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.096560
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