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Mixed backbone antisense oligonucleotides: design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments.

We have designed and synthesized mixed backbone oligonucleotides (MBOs) containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments. Thermal melting studies of the phosphodiester MBOs (three 2'-5'linkages at each end) with the complementary 3'-5'-DNA and -RN...

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Bibliografische gegevens
Hoofdauteurs: Kandimalla, E R, Manning, A, Zhao, Q, Shaw, D R, Byrn, R A, Sasisekharan, V, Agrawal, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC146429/
https://ncbi.nlm.nih.gov/pubmed/9016567
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