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Reduced mitochondrial coupling in vivo alters cellular energetics in aged mouse skeletal muscle

The mitochondrial theory of ageing proposes that the accumulation of oxidative damage to mitochondria leads to mitochondrial dysfunction and tissue degeneration with age. However, no consensus has emerged regarding the effects of ageing on mitochondrial function, particularly for mitochondrial coupl...

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Detalhes bibliográficos
Main Authors: Marcinek, David J, Schenkman, Kenneth A, Ciesielski, Wayne A, Lee, Donghoon, Conley, Kevin E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464247/
https://ncbi.nlm.nih.gov/pubmed/16254011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.097782
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