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Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo
Faster aging is predicted in more active tissues and animals because of greater reactive oxygen species generation. Yet age-related cell loss is greater in less active cell types, such as type II muscle fibers. Mitochondrial uncoupling has been proposed as a mechanism that reduces reactive oxygen sp...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1766336/ https://ncbi.nlm.nih.gov/pubmed/17215370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610131104 |
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