A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle

We tested the hypothesis that skeletal muscle ubiquitin–proteasome-dependent proteolysis is dysregulated in ageing in response to feeding. In Experiment 1 we measured rates of proteasome-dependent proteolysis in incubated muscles from 8- and 22-month-old rats, proteasome activities, and rates of ubi...

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Detalhes bibliográficos
Main Authors: Combaret, Lydie, Dardevet, Dominique, Rieu, Isabelle, Pouch, Marie-Noëlle, Béchet, Daniel, Taillandier, Daniel, Grizard, Jean, Attaix, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Cell Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464228/
https://ncbi.nlm.nih.gov/pubmed/16195315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.098004
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