Torbafylline (HWA 448) inhibits enhanced skeletal muscle ubiquitin-proteasome-dependent proteolysis in cancer and septic rats.

Eitemau Tebyg

• Ubiquitin–proteasome-dependent muscle proteolysis responds slowly to insulin release and refeeding in starved rats
  gan: Kee, Anthony J, et al.
  Cyhoeddwyd: (2003)
• Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.
  gan: Voisin, L, et al.
  Cyhoeddwyd: (1996)
• A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle
  gan: Combaret, Lydie, et al.
  Cyhoeddwyd: (2005)
• Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles.
  gan: Combaret, Lydie, et al.
  Cyhoeddwyd: (2004)
• Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin–proteasome and the caspase-dependent apoptotic pathways
  gan: Magne, Hugues, et al.
  Cyhoeddwyd: (2011)