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Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats

Ageing is characterized by a decline in muscle mass that could be explained by a defect in the regulation of postprandial muscle protein metabolism. Indeed, the stimulatory effect of food intake on protein synthesis and its inhibitory effect on proteolysis is blunted in old muscles from both animals...

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Autors principals: Rieu, Isabelle, Magne, Hugues, Savary-Auzeloux, Isabelle, Averous, Julien, Bos, Cécile, Peyron, M A, Combaret, Lydie, Dardevet, Dominique
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793878/
https://ncbi.nlm.nih.gov/pubmed/19752122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.178319
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