Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels

Genetic ablation of the fibroblast growth factor (Fgf) 14 gene in mice or a missense mutation in Fgf14 in humans causes ataxia and cognitive deficits. These phenotypes suggest that the neuronally expressed Fgf14 gene is essential for regulating normal neuronal activity. Here, we demonstrate that FGF...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lou, Jun-Yang, Laezza, Fernanda, Gerber, Benjamin R, Xiao, Maolei, Yamada, Kathryn A, Hartmann, Hali, Craig, Ann Marie, Nerbonne, Jeanne M, Ornitz, David M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2005
Schlagworte:
Cell Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464207/
https://ncbi.nlm.nih.gov/pubmed/16166153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.097220
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