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Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G(2)/M cell cycle arrest

BACKGROUND: New cancer therapeutic strategies must be investigated that enhance prostate cancer treatment while minimizing associated toxicities. We have previously shown that genistein, the major isoflavone found in soy, enhanced prostate cancer radiotherapy in vitro and in vivo. In this study, we...

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Autores principales: Raffoul, Julian J, Wang, Yu, Kucuk, Omer, Forman, Jeffrey D, Sarkar, Fazlul H, Hillman, Gilda G
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464148/
https://ncbi.nlm.nih.gov/pubmed/16640785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-107
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