Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G(2)/M cell cycle arrest

BACKGROUND: New cancer therapeutic strategies must be investigated that enhance prostate cancer treatment while minimizing associated toxicities. We have previously shown that genistein, the major isoflavone found in soy, enhanced prostate cancer radiotherapy in vitro and in vivo. In this study, we...

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Main Authors: Raffoul, Julian J, Wang, Yu, Kucuk, Omer, Forman, Jeffrey D, Sarkar, Fazlul H, Hillman, Gilda G
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464148/
https://ncbi.nlm.nih.gov/pubmed/16640785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-107
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