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Radiation-Induced HIF-1α Cell Survival Pathway is Inhibited by Soy Isoflavones in Prostate Cancer Cells
We previously showed that treatment of prostate cancer cells with soy isoflavones and radiation resulted in greater cell killing in vitro, and caused down-regulation of NF-κB and APE1/Ref-1. APE1/Ref-1 functions as a redox activator of transcription factors, including NF-κB and HIF-1α. These molecul...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670478/ https://ncbi.nlm.nih.gov/pubmed/19101986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24015 |
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