Radiation-Induced HIF-1α Cell Survival Pathway is Inhibited by Soy Isoflavones in Prostate Cancer Cells

We previously showed that treatment of prostate cancer cells with soy isoflavones and radiation resulted in greater cell killing in vitro, and caused down-regulation of NF-κB and APE1/Ref-1. APE1/Ref-1 functions as a redox activator of transcription factors, including NF-κB and HIF-1α. These molecul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Singh-Gupta, Vinita, Zhang, Hao, Banerjee, Sanjeev, Kong, Dejuan, Raffoul, Julian J., Sarkar, Fazlul H., Hillman, Gilda G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670478/
https://ncbi.nlm.nih.gov/pubmed/19101986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24015
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