Haplotype analysis suggest common founders in carriers of the recurrent BRCA2 mutation, 3398delAAAAG, in French Canadian hereditary breast and/ovarian cancer families

BACKGROUND: The 3398delAAAAG mutation in BRCA2 was recently found to recur in breast and/or ovarian cancer families from the French Canadian population of Quebec, a population that has genetic attributes consistent with a founder effect. To characterize the contribution of this mutation in this popu...

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Autors principals: Oros, Kathleen K, Leblanc, Guy, Arcand, Suzanna L, Shen, Zhen, Perret, Chantal, Mes-Masson, Anne-Marie, Foulkes, William D, Ghadirian, Parviz, Provencher, Diane, Tonin, Patricia N
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464093/
https://ncbi.nlm.nih.gov/pubmed/16539696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-23
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