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The influence of urinary pH on flecainide excretion and its serum pharmacokinetics.

The effect of urinary pH on flecainide excretion has been evaluated in six healthy subjects after a single oral dose of 300 mg flecainide administered as the acetate salt. The cumulative urinary excretion of unchanged flecainide under acidic conditions (134.0 +/- 16.1 mg; mean +/- s.e. mean) was sig...

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Detalhes bibliográficos
Main Authors: Muhiddin, K A, Johnston, A, Turner, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463395/
https://ncbi.nlm.nih.gov/pubmed/6326790
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