Influence of urine pH and urinary flow on the renal excretion of memantine

AIMS: The present study assessed the influence of urinary flow rate and urine pH on the renal excretion of the NMDA-receptor antagonist memantine. METHODS: In a randomized, open, four-period cross-over trial, 12 healthy male volunteers received 10 mg memantine daily for 43 days. After reaching stead...

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Bibliografiske detaljer
Main Authors: Freudenthaler, S, Meineke, I, Schreeb, K-H, Boakye, E, Gundert-Remy, U, Gleiter, C H
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1998
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873797/
https://ncbi.nlm.nih.gov/pubmed/9862242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00819.x
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