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Effects of β-adrenoceptor antagonists on the pharmacokinetics of lignocaine

1 In theory, β-adrenoceptor antagonists could lower the clearance of free lignocaine in three ways (a) by decreasing hepatic blood flow, (b) by competing for plasma binding sites or (c) by inhibiting the enzymes responsible for metabolising lignocaine. 2 The first mechanism has been demonstrated for...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tucker, G. T., Bax, N. D. S., Lennard, M. S., Al-Asady, S., Bharaj, H. S., Woods, H. F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1984
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463282/
https://ncbi.nlm.nih.gov/pubmed/6146336
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