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Effects of β-adrenoceptor antagonists on the pharmacokinetics of lignocaine
1 In theory, β-adrenoceptor antagonists could lower the clearance of free lignocaine in three ways (a) by decreasing hepatic blood flow, (b) by competing for plasma binding sites or (c) by inhibiting the enzymes responsible for metabolising lignocaine. 2 The first mechanism has been demonstrated for...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1984
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1463282/ https://ncbi.nlm.nih.gov/pubmed/6146336 |
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