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Primer initiation and extension by T7 DNA primase
T7 DNA primase is composed of a catalytic RNA polymerase domain (RPD) and a zinc-binding domain (ZBD) connected by an unstructured linker. The two domains are required to initiate the synthesis of the diribonucleotide pppAC and its extension into a functional primer pppACCC (de novo synthesis), as w...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462978/ https://ncbi.nlm.nih.gov/pubmed/16642036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601112 |
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