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Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7

The DNA helicase encoded by bacteriophage T7 consists of six identical subunits that form a ring through which the DNA passes. Binding of ssDNA is a prior step to translocation and unwinding of DNA by the helicase. Arg-493 is located at a conserved structural motif within the interior cavity of the...

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Detalhes bibliográficos
Main Authors: Lee, Seung-Joo, Qimron, Udi, Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2449338/
https://ncbi.nlm.nih.gov/pubmed/18574147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802732105
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