Phospholipase Cγ/diacylglycerol-dependent activation of β2-chimaerin restricts EGF-induced Rac signaling

Although receptor-mediated regulation of small G-proteins and the cytoskeleton is intensively studied, the mechanisms for attenuation of these signals are poorly understood. In this study, we have identified the Rac-GAP β2-chimaerin as an effector of the epidermal growth factor receptor (EGFR) via c...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, HongBin, Yang, Chengfeng, Leskow, Federico Coluccio, Sun, Jing, Canagarajah, Bertram, Hurley, James H, Kazanietz, Marcelo G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462969/
https://ncbi.nlm.nih.gov/pubmed/16628218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601098
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