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Neutrophils and their Fcγ receptors are essential in a mouse model of transfusion-related acute lung injury

Transfusion-related acute lung injury (TRALI) is the most common cause of transfusion-related mortality. To explore the pathogenesis of TRALI, we developed an in vivo mouse model based on the passive transfusion of an MHC class I (MHC I) mAb (H2K(d)) to mice with the cognate antigen. Transfusion of...

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Autors principals: Looney, Mark R., Su, Xiao, Van Ziffle, Jessica A., Lowell, Clifford A., Matthay, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462945/
https://ncbi.nlm.nih.gov/pubmed/16710475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27238
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