Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury

Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-associated mortality in the US. Previously, we established an immune-mediated TRALI mouse model, wherein mice with cognate antigen were challenged with MHC class I mAb. In this study, when mice housed in a rodent, spec...

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Detalhes bibliográficos
Main Authors: Looney, Mark R., Nguyen, John X., Hu, Yongmei, Van Ziffle, Jessica A., Lowell, Clifford A., Matthay, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769181/
https://ncbi.nlm.nih.gov/pubmed/19809160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38432
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