Genetic platelet depletion is superior in platelet transfusion compared to current models

Genetically modified mice have advanced our knowledge on platelets in hemostasis and beyond tremendously. However, mouse models harbor certain limitations, including availability of platelet specific transgenic strains, and off-target effects on other cell types. Transfusion of genetically modified...

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Publicado en:Haematologica
Main Authors: Salzmann, Manuel, Schrottmaier, Waltraud C., Kral-Pointner, Julia B., Mussbacher, Marion, Volz, Julia, Hoesel, Bastian, Moser, Bernhard, Bleichert, Sonja, Morava, Susanne, Nieswandt, Bernhard, Schmid, Johannes A., Assinger, Alice
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2020
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271594/
https://ncbi.nlm.nih.gov/pubmed/31537686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.222448
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