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In vitro reconstitution of mammalian U1 snRNPs active in splicing: the U1-C protein enhances the formation of early (E) spliceosomal complexes.

We have established an in vitro reconstitution/splicing complementation system which has allowed the investigation of the role of mammalian U1 snRNP components both in splicing and at the early stages of spliceosome formation. U1 snRNPs reconstituted from purified, native snRNP proteins and either a...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Will, C L, Rümpler, S, Klein Gunnewiek, J, van Venrooij, W J, Lührmann, R
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146292/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972845/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.23.4614
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