In vitro reconstitution of mammalian U1 snRNPs active in splicing: the U1-C protein enhances the formation of early (E) spliceosomal complexes.

We have established an in vitro reconstitution/splicing complementation system which has allowed the investigation of the role of mammalian U1 snRNP components both in splicing and at the early stages of spliceosome formation. U1 snRNPs reconstituted from purified, native snRNP proteins and either a...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Will, C L, Rümpler, S, Klein Gunnewiek, J, van Venrooij, W J, Lührmann, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.23.4614
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