In vitro reconstitution of mammalian U1 snRNPs active in splicing: the U1-C protein enhances the formation of early (E) spliceosomal complexes.

We have established an in vitro reconstitution/splicing complementation system which has allowed the investigation of the role of mammalian U1 snRNP components both in splicing and at the early stages of spliceosome formation. U1 snRNPs reconstituted from purified, native snRNP proteins and either a...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Will, C L, Rümpler, S, Klein Gunnewiek, J, van Venrooij, W J, Lührmann, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.23.4614
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