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Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene

The Nrf2 (nuclear factor-erythroid 2 p45-related factor 2) transcription factor regulates gene expression of the GCLC (glutamate–cysteine ligase catalytic subunit), which is a key enzyme in glutathione synthesis, and GSTs (glutathione S-transferases) via the ARE (antioxidant-response element). The M...

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Autors principals: Vollrath, Valeska, Wielandt, Ana M., Iruretagoyena, Mirentxu, Chianale, Jose
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462684/
https://ncbi.nlm.nih.gov/pubmed/16426233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051518
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