Characterization of a protein recognizing minor groove binders-damaged DNA.

By using electromobility shift assay (EMSA), we have identified a protein able to recognize the DNA only if it was previously reacted with minor groove binders. This protein binds with very high affinity AT containing DNA treated with minor groove binders such as distamycin A, Hoechst 33258 and 3334...

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Bibliographic Details
Main Authors: Colella, G, Bonfanti, M, D'Incalci, M, Broggini, M
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC146256/
https://ncbi.nlm.nih.gov/pubmed/8932377
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