Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice.

We have investigated the transcriptional regulation of the human embryonic zeta-globin gene promoter. First, we examined the effect that deletion of sequences 5' to zeta-globin's CCAAT box have on zeta-promoter activity in erythroid cell lines. Deletions of sequences between -116 and -556 (cap = 0)...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Pondel, M D, Sharpe, J A, Clark, S, Pearson, L, Wood, W G, Proudfoot, N J
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 1996
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8932366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.21.4158
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