Escherichia coli strains (ndk) lacking nucleoside diphosphate kinase are powerful mutators for base substitutions and frameshifts in mismatch-repair-deficient strains.

Nucleoside diphosphate (NDP) kinase is one of the enzymes that maintains triphosphate pools. Escherichia coli strains (ndk) lacking this enzyme have been shown to be modest base substitution mutators, and two members of the human family of NDP kinases act as tumor suppressors. We show here that in E...

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Bibliografiska uppgifter
Huvudupphovsmän: Miller, Jeffrey H, Funchain, Pauline, Clendenin, Wendy, Huang, Tiffany, Nguyen, Anh, Wolff, Erika, Yeung, Annie, Chiang, Ju-Huei, Garibyan, Lilit, Slupska, Malgorzata M, Yang, Hanjing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462255/
https://ncbi.nlm.nih.gov/pubmed/12242219
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