Escherichia coli strains (ndk) lacking nucleoside diphosphate kinase are powerful mutators for base substitutions and frameshifts in mismatch-repair-deficient strains.

Nucleoside diphosphate (NDP) kinase is one of the enzymes that maintains triphosphate pools. Escherichia coli strains (ndk) lacking this enzyme have been shown to be modest base substitution mutators, and two members of the human family of NDP kinases act as tumor suppressors. We show here that in E...

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Detalhes bibliográficos
Main Authors: Miller, Jeffrey H, Funchain, Pauline, Clendenin, Wendy, Huang, Tiffany, Nguyen, Anh, Wolff, Erika, Yeung, Annie, Chiang, Ju-Huei, Garibyan, Lilit, Slupska, Malgorzata M, Yang, Hanjing
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462255/
https://ncbi.nlm.nih.gov/pubmed/12242219
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