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Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster.

A transgenic system ("FLP-out") based on yeast FLP recombinase allowed induced overexpression of MnSOD enzyme in adult Drosophila melanogaster. With FLP-out a brief heat pulse (HP) of young, adult flies triggered the rearrangement and subsequent expression of a MnSOD transgene throughout t...

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Autors principals: Sun, Jingtao, Folk, Donna, Bradley, Timothy J, Tower, John
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462135/
https://ncbi.nlm.nih.gov/pubmed/12072463
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