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Multiple effects of genetic background on variegated transgene expression in mice.

BLG/7 transgenic mice express an ovine beta-lactoglobulin transgene during lactation. Unusually, transgene expression levels in milk differ between siblings. This variable expression is due to variegated transgene expression in the mammary gland and is reminiscent of position-effect variegation. The...

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Détails bibliographiques
Auteurs principaux: Opsahl, Margaret L, McClenaghan, Margaret, Springbett, Anthea, Reid, Sarah, Lathe, Richard, Colman, Alan, Whitelaw, C Bruce A
Format: Artigo
Langue:Inglês
Publié: 2002
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462007/
https://ncbi.nlm.nih.gov/pubmed/11901126
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