A carregar...

Telomeric and rDNA silencing in Saccharomyces cerevisiae are dependent on a nuclear NAD(+) salvage pathway.

The Sir2 protein is an NAD(+)-dependent protein deacetylase that is required for silencing at the silent mating-type loci, telomeres, and the ribosomal DNA (rDNA). Mutations in the NAD(+) salvage gene NPT1 weaken all three forms of silencing and also cause a reduction in the intracellular NAD(+) lev...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sandmeier, Joseph J, Celic, Ivana, Boeke, Jef D, Smith, Jeffrey S
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462005/
https://ncbi.nlm.nih.gov/pubmed/11901108
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!