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Differential Nuclear Localization Does Not Determine the Silencing Status of Saccharomyces cerevisiae Telomeres

In Saccharomyces cerevisiae, genes near telomeres are transcriptionally repressed, a phenomenon termed telomere position effect (TPE). Yeast telomeres cluster near the nuclear periphery, as do foci of proteins essential for TPE: Rap1p, Sir2-4p, and yKu70p/yKu80p. However, it is not clear if localiza...

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Detalhes bibliográficos
Main Authors: Mondoux, Michelle A., Scaife, Jillian G., Zakian, Virginia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219492/
https://ncbi.nlm.nih.gov/pubmed/18073421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.079848
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