Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates.

The protein kinase Raf is an important signaling protein. Raf activation is initiated by an interaction with GTP-bound Ras, and Raf functions in signal transmission by phosphorylating and activating a mitogen-activated protein (MAP) kinase kinase named MEK. We identified 13 mutations in the Caenorha...

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Bibliografiska uppgifter
Huvudupphovsmän: Hsu, Virginia, Zobel, Cheri L, Lambie, Eric J, Schedl, Tim, Kornfeld, Kerry
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461998/
https://ncbi.nlm.nih.gov/pubmed/11861555
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