Identification of a mutant DNA polymerase delta in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations.

We propose that a beta-turn-beta structure, which plays a critical role in exonucleolytic proofreading in the bacteriophage T4 DNA polymerase, is also present in the Saccharomyces cerevisiae DNA pol delta. Site-directed mutagenesis was used to test this proposal by introducing a mutation into the ye...

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Библиографические подробности
Главные авторы: Hadjimarcou, M I, Kokoska, R J, Petes, T D, Reha-Krantz, L J
Формат: Artigo
Язык:Inglês
Опубликовано: 2001
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461621/
https://ncbi.nlm.nih.gov/pubmed/11333228
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