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A polyoma-based episomal vector efficiently expresses exogenous genes in mouse embryonic stem cells.

We describe the ability of novel episomally maintained vectors to efficiently promote gene expression in embryonic stem (ES) cells as well as in established mouse cell lines. Extrachromosomal maintenance of our vectors is based on the presence of polyoma virus DNA sequences, including the origin of...

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Hlavní autoři: Camenisch, G, Gruber, M, Donoho, G, Van Sloun, P, Wenger, R H, Gassmann, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC146162/
https://ncbi.nlm.nih.gov/pubmed/8871548
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