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Population Genetics of Translational Robustness

Recent work has shown that expression level is the main predictor of a gene's evolutionary rate and that more highly expressed genes evolve slower. A possible explanation for this observation is selection for proteins that fold properly despite mistranslation, in short selection for translation...

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Detalhes bibliográficos
Main Authors: Wilke, Claus O., Drummond, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461446/
https://ncbi.nlm.nih.gov/pubmed/16489231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.051300
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