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Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesis.

RVR/Rev-erb beta/BD73 is an orphan steroid receptor that has no known ligand in the "classical' sense. RVR binds as a monomer to an element which consists of an A/T-rich sequence upstream of the consensus hexameric half-site. However, RVR does not activate transcription and blocks transact...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Burke, L, Downes, M, Carozzi, A, Giguère, V, Muscat, G E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC146133/
https://ncbi.nlm.nih.gov/pubmed/8836172
Etiketler: Etiketle
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