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Methylation inhibitors can increase the rate of cytosine deamination by (cytosine-5)-DNA methyltransferase.

The target cytosines of (cytosine-5)-DNA methyltransferases in prokaryotic and eukaryotic DNA show increased rates of C-->T transition mutations compared to non-target cytosines. These mutations are induced either by the spontaneous deamination of 5-mC-->T generating inefficiently repaired G:T rathe...

Whakaahuatanga katoa

I tiakina i:
I whakaputaina i:Nucleic Acids Res
Ngā kaituhi matua: Zingg, J M, Shen, J C, Yang, A S, Rapoport, H, Jones, P A
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 1996
Ngā marau:
Research Article
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8774911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.16.3267
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