Bi-directional gene switching with the tetracycline repressor and a novel tetracycline antagonist.
We have screened a panel of tetracycline (tc)-like compounds for their potential use with tc-repressor (tetR) based gene switches. The interaction between tc and tetR appears quite specific, as only tc itself and its close homologues anhydro-tc and doxycycline strongly inhibited DNA binding. However...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.2900 |
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