Cleavage of oligodeoxyribonucleotides from controlled-pore glass supports and their rapid deprotection by gaseous amines.

A novel method for the deprotection of oligodeoxyribonucleotides has been developed. Gaseous amines such as ammonia or methylamine were employed under pressure to achieve mild and rapid deprotection conditions. For example, oligodeoxyribonucleotides having a (tert-butyl)phenoxyacetyl group for the p...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Boal, J H, Wilk, A, Harindranath, N, Max, E E, Kempe, T, Beaucage, S L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.3115
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!