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Functional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoter.

HOX A genes are induced in a temporal fashion after retinoic acid (RA) treatment in non-N-ras-transformed PA-1 human teratcarcinoma cells. However, In N-ras-transformed PA-1 cells, RA-Induced expression of HOX A genes is delayed. The mRNA for the transcriptional activator AP-2 is overexpressed in th...

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Detalhes bibliográficos
Main Authors: Doerksen, L F, Bhattacharya, A, Kannan, P, Pratt, D, Tainsky, M A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146022/
https://ncbi.nlm.nih.gov/pubmed/8759021
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