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Functional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoter.

HOX A genes are induced in a temporal fashion after retinoic acid (RA) treatment in non-N-ras-transformed PA-1 human teratcarcinoma cells. However, In N-ras-transformed PA-1 cells, RA-Induced expression of HOX A genes is delayed. The mRNA for the transcriptional activator AP-2 is overexpressed in th...

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Udgivet i:Nucleic Acids Res
Principais autores: Doerksen, L F, Bhattacharya, A, Kannan, P, Pratt, D, Tainsky, M A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8759021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.14.2849
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