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Evaluation of Multiplex Flow Cytometric Opsonophagocytic Assays for Determination of Functional Anticapsular Antibodies to Streptococcus pneumoniae

The determination of functional antipneumococcal capsular polysaccharide antibodies by sequential testing of pre- and postvaccination serum samples one serotype at a time is sample-intensive and time-consuming and has a relatively low throughput. We tested several opsonophagocytic assay (OPA) format...

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Bibliografiske detaljer
Main Authors: Martinez, Joseph E., Clutterbuck, Elizabeth A., Li, Han, Romero-Steiner, Sandra, Carlone, George M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459634/
https://ncbi.nlm.nih.gov/pubmed/16603613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.13.4.459-466.2006
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