Multilaboratory Evaluation of a Viability Assay for Measurement of Opsonophagocytic Antibodies Specific to the Capsular Polysaccharides of Streptococcus pneumoniae

Opsonophagocytosis is a correlate of protection that measures the functional activity of vaccine-induced antibodies. A standardized opsonophagocytosis assay (OPA) should be used as part of the evaluation of current and future pneumococcal (Pnc) polysaccharide (Ps)-based vaccines. We enrolled five la...

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Main Authors: Romero-Steiner, Sandra, Frasch, Carl, Concepcion, Nelydia, Goldblatt, David, Käyhty, Helena, Väkeväinen, Merja, Laferriere, Craig, Wauters, Dominique, Nahm, Moon H., Schinsky, Mark F., Plikaytis, Brian D., Carlone, George M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
主題:
Microbial Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC262452/
https://ncbi.nlm.nih.gov/pubmed/14607861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.10.6.1019-1024.2003
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