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Aβ-induced meningoencephalitis is IFN-γ-dependent and is associated with T cell-dependent clearance of Aβ in a mouse model of Alzheimer's disease
Vaccination against amyloid β-peptide (Aβ) has been shown to be successful in reducing Aβ burden and neurotoxicity in mouse models of Alzheimer's disease (AD). However, although Aβ immunization did not show T cell infiltrates in the brain of these mice, an Aβ vaccination trial resulted in menin...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458792/ https://ncbi.nlm.nih.gov/pubmed/16549802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506209103 |
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